The musculoskeletal system
A Case Study on Bone Tissue Structure and Repair Alice Smith is a 39-year-old female who works for an airline manufacturing plant. While she was at work today a large box of metal rivets fell from a 20-ft.-high overhead shelf, striking her outstretched arm and knocking her to the ground. The ambulance personnel reported that she had lost quite a bit of blood at the accident scene and was “knocked out” with head injuries when they arrived. To minimize further hemorrhage, the paramedics applied a pressure bandage to her arm. You meet the paramedics as they bring Alice into the emergency room and begin to assess her for injuries. She is awake and alert, but complaining of severe left arm and back pain, plus she has a “killer headache.” To fully examine her injuries you remove four blood-soaked bandages from her arm. You notice a large open wound on her arm with what appears to be bone tissue sticking out of the skin. She also has bruises covering her left shoulder, left wrist, and lower back. To determine the extent of her injuries Alice undergoes several x-rays, which reveal the following: fracture of the left humerus at the proximal diaphysis, depressed fracture of the occipital bone, fracture of the 3rd lumbar vertebral body. Discussion Questions: Case Study #9a: Pick 3 of the 5 Questions to answer. One way bones are classified is by their shape. How would you classify the bones fractured of Alice? The diaphysis of Alice’s humerus is fractured. What type of bone makes up the majority of the diaphysis of long bones like the humerus? Describe the layers of bone tissue found here. Within days after a fracture, a “soft callus” of fibrocartilage forms. What fibers are found in this type of cartilage? Identify the cells required for fibrocartilaginous callus formation and list their functions. As a fracture is repaired, new bone is added to the injury site. What term is used to describe the addition of new bone tissue? Identify which bone cell is responsible for this process and explain how it occurs. In the final stage of bone repair, some of the osseous tissue must be broken down and removed. What term is used to define the breaking down of osseous tissue? Which bone cell would be best suited for this task? Case Study #9b Muscle Limb Girdle Muscular Dystrophy AGE:29 Gender:Male DIAGNOSIS: Limb Girdle Muscular Dystrophy (LGMD) Patient History: 6 Years ago, developed progressive weakness in his limb muscles. The Neurologist diagnosed LGMD.

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